Investigation of characteristic hemodynamic parameters indicating thinning and thickening sites of cerebral aneurysms

Cellular and animal experiments and computational fluid dynamics (CFD) have revealed that mechanisms of the initiation, growth and rupture of a cerebral aneurysm are related to hemodynamics.By direct observation of a cerebral aneurysm during craniotomy, thinning or thickening sites can be found on the aneurysmal wall.The thinning site of a cerebral

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Arachidonic Acid Metabolism Pathway Is Not Only Dominant in Metabolic Modulation but Associated With Phenotypic Variation After Acute Hypoxia Exposure

Background: The modulation of arachidonic acid (AA) metabolism pathway is identified in metabolic alterations after hypoxia exposure, but its biological function is controversial.We aimed at integrating plasma metabolomic and transcriptomic approaches to systematically explore the roles of the AA Carseat 0-4 metabolism pathway in response to acute

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